Symbol
Name
ID

Brca1
breast cancer 1, early onset
MGI:104537

Phenotype annotations related to digestive/alimentary system

Darker colors indicate more annotations

Human Phenotypes

Tracheoesophageal fistula

Aganglionic megacolon

Hereditary nonpolyposis colorectal carcinoma

Colon cancer

Duodenal stenosis

Meckel diverticulum

Intestinal pseudo-obstruction

Neoplasm of the stomach

Stomach cancer

Intermittent diarrhea

Nausea and vomiting

Functional intestinal obstruction

Neoplasm of the liver

Disease(s) Associated with BRCA1

colorectal cancer

Fanconi anemia

pancreatic cancer

stomach cancer

Mouse Phenotypes		abnormal small intestinal villus morphology	decreased small intestinal villus height	increased mouth tumor incidence	increased salivary adenocarcinoma incidence
Availability	Mouse Genotype	abnormal small intestinal villus morphology	decreased small intestinal villus height	increased mouth tumor incidence	increased salivary adenocarcinoma incidence
	Brca1^tm5.1Cxd/Brca1^tm5.1Cxd
	Brca1^tm1Aash/Brca1^tm1Aash Tg(LGB-cre)74Acl/0 (conditional)
	Brca1^tm1Cxd/Brca1^tm2Cxd Tg(KRT5-cre)5132Jlj/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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